Mostowy Lab

An automated microscopy workflow to study Shigella-neutrophil interactions and antibiotic efficacy in vivo.

Lensen A, Gomes MC, López-Jiménez AT, Mostowy S

Disease Models & Mechanisms, 2023, 16 (6)

Septins and K63 ubiquitin chains are present in separate bacterial microdomains during autophagy of entrapped Shigella.

Lobato-Márquez D, Conesa JJ, López-Jiménez AT, Divine ME, Pruneda JN, Mostowy S

Journal of Cell Science, 2023, 136 (7)

Zebrafish null mutants of Sept6 and Sept15 are viable but more susceptible to Shigella infection.

Torraca V, Bielecka MK, Gomes MC, Brokatzky D, Busch-Nentwich EM, Mostowy S

Cytoskeleton (Hoboken, N.J.), 2023

The septin cytoskeleton: Heteromer composition defines filament function.

Güler GÖ, Mostowy S

The Journal of Cell Biology, 2023, 222 (3)

P1 Bacteriophage-Enabled Delivery of CRISPR-Cas9 Antimicrobial Activity Against Shigella flexneri.

Huan YW, Torraca V, Brown R, Fa-Arun J, Miles SL, Oyarzún DA, Mostowy S, Wang B

ACS Synthetic Biology, 2023

Proximity proteomics identifies septins and PAK2 as decisive regulators of actomyosin-mediated expulsion of von Willebrand factor.

El-Mansi S, Robinson CL, Kostelnik KB, McCormack JJ, Mitchell TP, Lobato-Márquez D, Rajeeve V, Cutillas P, Cutler DF, Mostowy S, Nightingale TD

Blood, 2023, 141 (8), 930-944

Louis Pasteur continues to shape the future of microbiology.

Mostowy S

Disease Models & Mechanisms, 2022, 15 (12)

Pyroptosis in host defence against bacterial infection.

Brokatzky D, Mostowy S

Disease Models & Mechanisms, 2022, 15 (7)

Septins promote caspase activity and coordinate mitochondrial apoptosis.

Ngo HV, Robertin S, Brokatzky D, Bielecka MK, Lobato-Márquez D, Torraca V, Mostowy S

Cytoskeleton (Hoboken, N.J.), 2022

Emerging technologies and infection models in cellular microbiology.

López-Jiménez AT, Mostowy S

Nature Communications, 2021, 12 (1), 6764