Mostowy Lab

Septins and K63 chains form separate bacterial microdomains during autophagy of entrapped Shigella.

Lobato-Márquez D, Conesa JJ, López-Jiménez AT, Divine ME, Pruneda JN, Mostowy S

Journal of Cell Science, 2023

Zebrafish null mutants of Sept6 and Sept15 are viable but more susceptible to Shigella infection.

Torraca V, Bielecka MK, Gomes MC, Brokatzky D, Busch-Nentwich EM, Mostowy S

Cytoskeleton (Hoboken, N.J.), 2023

The septin cytoskeleton: Heteromer composition defines filament function.

Güler GÖ, Mostowy S

The Journal of Cell Biology, 2023, 222 (3)

P1 Bacteriophage-Enabled Delivery of CRISPR-Cas9 Antimicrobial Activity Against Shigella flexneri.

Huan YW, Torraca V, Brown R, Fa-Arun J, Miles SL, Oyarzún DA, Mostowy S, Wang B

ACS Synthetic Biology, 2023

Proximity proteomics identifies septins and PAK2 as decisive regulators of actomyosin-mediated expulsion of von Willebrand factor.

El-Mansi S, Robinson CL, Kostelnik KB, McCormack JJ, Mitchell TP, Lobato-Márquez D, Rajeeve V, Cutillas P, Cutler DF, Mostowy S, Nightingale TD

Blood, 2023, 141 (8), 930-944

Louis Pasteur continues to shape the future of microbiology.

Mostowy S

Disease Models & Mechanisms, 2022, 15 (12)

Pyroptosis in host defence against bacterial infection.

Brokatzky D, Mostowy S

Disease Models & Mechanisms, 2022, 15 (7)

Septins promote caspase activity and coordinate mitochondrial apoptosis.

Ngo HV, Robertin S, Brokatzky D, Bielecka MK, Lobato-Márquez D, Torraca V, Mostowy S

Cytoskeleton (Hoboken, N.J.), 2022

Emerging technologies and infection models in cellular microbiology.

López-Jiménez AT, Mostowy S

Nature Communications, 2021, 12 (1), 6764

Mechanistic insight into bacterial entrapment by septin cage reconstitution.

Lobato-Márquez D, Xu J, Güler GÖ, Ojiakor A, Pilhofer M, Mostowy S

Nature Communications, 2021, 12 (1), 4511