Mostowy Lab

High-content high-resolution microscopy and deep learning-assisted analysis reveals host and bacterial heterogeneity during Shigella infection.

López-Jiménez AT, Brokatzky D, Pillay K, Williams T, Özbaykal Güler G, Mostowy S

ELife, 2025, 13

Novel and unscrutinized immune entities of the zebrafish gut.

Andersen-Civil AIS, Mantel M, Soh J, Mostowy S, Brugman S, Vanwalleghem GC

FEBS Letters, 2025

Comparative Analysis of Septin Modifiers, Forchlorfenuron and UR214-9, on Mitochondrial Fragmentation and Lytic Cell Death.

Brokatzky D, Das R, Painter H, Singh RK, Mostowy S

Cytoskeleton (Hoboken, N.J.), 2025

Neutrophils display antibacterial defense via non-canonical LC3 decoration of extracellular bacteria.

Skerniskyte J, Barroso MV, Chicher J, Hammann P, Demais V, Wright K, Mostowy S, Marteyn BS

Microbes and Infection, 2025, 105545

Organoid models advance dysentery control.

Miles SL, Mostowy S

Nature Genetics, 2025

Shigella-trained pro-inflammatory macrophages protect zebrafish from secondary infection.

Gomes MC, Brokatzky D, Mostowy S

Cell Reports, 2025, 44 (5), 115601

ERK activation waves coordinate mechanical cell competition leading to collective elimination via extrusion of bacterially infected cells.

Hundsdorfer L, Muenkel M, Aparicio-Yuste R, Sanchez-Rendon JC, Gomez-Benito MJ, Balmes A, Schäffer TE, Velic A, Yeh YT, Constantinou I, Wright K, Özbaykal Güler G, Brokatzky D, Maček B, Mostowy S, Bastounis EE

Cell Reports, 2025, 44 (1), 115193

Emerging models to study competitive interactions within bacterial communities.

Virgo M, Mostowy S, Ho BT

Trends in Microbiology, 2025

Shigella sonnei: epidemiology, evolution, pathogenesis, resistance and host interactions.

Scott TA, Baker KS, Trotter C, Jenkins C, Mostowy S, Hawkey J, Schmidt H, Holt KE, Thomson NR, Baker S

Nature Reviews. Microbiology, 2025, 23 (5), 303-317

Rearranging to resist cell death.

Brokatzky D, Mostowy S

ELife, 2024, 13